# DBT JRF 2020 — Question 19

Exam: DBT JRF 2020 · Section: B · Topic: Biochemistry · Difficulty: Medium

## Question

The probe used to analyse glycoproteins is

## Options

- **A.** cytokine
- **B.** interferons
- **C.** lectins
- **D.** glutens

## Answer

Option C

## Explanation

Endoreduplication (endoreplication): repeated rounds of DNA replication (S phase) occur without subsequent mitosis (M phase) or cytokinesis, resulting in a polyploid nucleus within a single cell. The cell cycle oscillates between G1 and S phases only. This produces gigantic cells with massively amplified genomes. Biological examples: Arabidopsis leaf epidermal cells (up to 32C or 64C); Drosophila salivary gland cells (polytene chromosomes up to 1024C); mammalian megakaryocytes (up to 128N, producing platelets by cytoplasmic fragmentation); maize endosperm cells; tapetum cells of anther. Endoreduplication is distinct from polyploidisation by cell fusion (autopolyploidy).

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