# DBT JRF 2020 — Question 31

Exam: DBT JRF 2020 · Section: B · Topic: Genetics · Difficulty: Medium

## Question

Which of the following disorders does not show sex-linked inheritance?

## Options

- **A.** Haemophilia B
- **B.** Haemophilia A
- **C.** Tay-Sachs disease
- **D.** Duchenne muscular dystrophy

## Answer

Option C

## Explanation

Yield coefficient calculation for Saccharomyces cerevisiae in fed-batch culture. Cell yield coefficient $Y_{X/S}$ = mass of cells produced per mass of substrate consumed. Using the relationship: $\dfrac{dX}{dt} = \mu X$ and $\dfrac{dS}{dt} = -\dfrac{\mu X}{Y_{X/S}}$ . Therefore $Y_{X/S} = \dfrac{\mu X}{q_S}$ , where $q_S$ = volumetric substrate uptake rate. $Y_{X/S} = \dfrac{\mu \times X}{q_S} = \dfrac{0.4 \text{ h}^{-1} \times 30 \text{ g L}^{-1}}{18 \text{ g L}^{-1}\text{h}^{-1}} = \dfrac{12}{18} = 0.667 \approx 0.67 \text{ g cells / g substrate}$ .

Source: https://mypyqbuddy.com/questions/which-of-the-following-disorders-does-not-show-6a05a8a02adafec470293237