# DBT JRF 2022 — Question 9

Exam: DBT JRF 2022 · Section: A · Topic: Molecular Biology › RNA Polymerase II & Gene Transcription · Difficulty: Medium

## Question

Eukaryotic RNA Polymerase II transcribes:

## Options

- **A.** rRNA and tRNA genes
- **B.** mRNA and tRNA genes
- **C.** mRNA and 5S rRNA genes
- **D.** mRNA, miRNA and snRNA genes

## Answer

Option D

## Explanation

Transcription by RNA Polymerase II: RNA Polymerase II (Pol II) is responsible for transcribing: • Protein-coding genes → mRNA (messenger RNA) • MicroRNA genes → pre-miRNA (processed to mature miRNA regulating gene expression) • Small nuclear RNA genes → snRNA (components of the spliceosome) Pol I transcribes: 18S, 5.8S, 28S rRNA (large ribosomal RNA genes) Pol III transcribes: tRNA genes, 5S rRNA gene, and some other small non-coding RNAs The question asks specifically about Pol II; Option 4 (mRNA, miRNA, and snRNA) is the most complete and accurate answer.

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