# DBT JRF 2022 — Question 53

Exam: DBT JRF 2022 · Section: B · Topic: Microbiology › Parasitology - Plasmodium Life Cycle · Difficulty: Medium

## Question

Which form of the plasmodia is transmitted from mosquito to human?

## Options

- **A.** Sporozoite
- **B.** Gametocyte
- **C.** Merozoite
- **D.** Hypnozoite

## Answer

Option A

## Explanation

Plasmodium sporozoite location in mosquito: Life cycle of Plasmodium (malaria parasite) in the Anopheles mosquito vector: 1. When a mosquito takes a blood meal from an infected human, it ingests gametocytes. 2. Gametocytes mature into gametes → fertilisation → ookinete → oocyst (in midgut wall). 3. Oocysts rupture → release sporozoites → sporozoites MIGRATE to the SALIVARY GLANDS. 4. When the infected mosquito bites a new human, sporozoites are INJECTED with saliva into the bloodstream. 5. Sporozoites travel to the LIVER (exoerythrocytic stage), infect hepatocytes, multiply, and later release merozoites into the blood. Conclusion: Sporozoites are found in the SALIVARY GLANDS of the Anopheles mosquito. Answer: Sporozoites in salivary glands of infected Anopheles mosquito.

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