# DBT JRF 2022 — Question 61

Exam: DBT JRF 2022 · Section: B · Topic: Microbiology › Microbiology Concepts - Match the Following · Difficulty: Medium

## Question

Match items in List I with items in List II.
| List 1 (Syndrome) | List 2 (Karyotype) |
| --- | --- |
| (A) Down Syndrome | I. Trisomy 18 |
| (B) Edward Syndrome | II. XXY |
| (C) Klinefelter Syndrome | III. Female with one X |
| (D) Turner Syndrome | IV. XX+21 |
 Choose the correct answer from the options given below :

## Options

- **A.** A-I, B-IV, C-II, D-III
- **B.** A-IV, B-II, C-III, D-I
- **C.** A-IV, B-I, C-II, D-III
- **D.** A-III, B-I, C-IV, D-II

## Answer

Option C

## Explanation

Matching stem cell types with potency  : Stem cell potency hierarchy: • Totipotent: Can form any cell type including placenta (trophoblast); only zygote and early blastomeres are totipotent. • Pluripotent: Can form all three germ layers (ectoderm, mesoderm, endoderm) but NOT placenta; embryonic stem cells (ESCs), iPSCs. • Multipotent: Can form multiple cell types within a lineage; e.g., haematopoietic stem cells (all blood cells), neural stem cells. • Unipotent: Can form only one cell type; e.g., skin stem cells forming only keratinocytes. The correct matching A-IV, B-I, C-II, D-III pairs the stem cell types in List I with their potency definitions in List II. Answer: A-IV, B-I, C-II, D-III (per the answer key).

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