One centimorgan is defined as the genetic distance between two loci with a statistically corrected recombination frequency of
One centimorgan is defined as the genetic distance between two loci with a statistically corrected recombination frequency of
Select an option to attempt
Correct Answer: Option D
Explanation
Lectins are carbohydrate-binding proteins/glycoproteins of non-immune origin that bind specifically and non-covalently to particular mono- or oligosaccharide structures. They are used as probes in glycobiology: Concanavalin A (Con A) → α-D-mannose, α-D-glucose; Wheat Germ Agglutinin (WGA) → GlcNAc, sialic acid; Peanut Agglutinin (PNA) → β-Gal-(1→3)-GalNAc. Lectin blotting (similar to Western blotting) resolves glycoproteins by SDS-PAGE, transfers to membrane, and detects with labelled lectins — revealing the glycan composition and pattern (glycoform). Lectins can also be used in affinity chromatography to purify glycoproteins.