Primary cilia biogenesis typically starts at the
Primary cilia biogenesis typically starts at the
Select an option to attempt
Correct Answer: Option B
Explanation
Primary cilia are microtubule-based sensory organelles that assemble from the basal body (a modified centriole) and project from the cell surface. Their biogenesis is tightly linked to the cell cycle. During S phase and G2/M, centrioles are engaged in centrosome duplication and mitotic spindle formation — they cannot simultaneously form a basal body. Ciliogenesis therefore occurs in G1 or G0 (quiescent) phase, after cells exit mitosis. The primary cilium is resorbed at the G1/S transition before cell division resumes, coordinated by Aurora A kinase and HEF1 signalling.