The cytosine residues in the DNA are methylated at specific di- or trinucleotide sequences. Which among these methylation motifs are found…
The cytosine residues in the DNA are methylated at specific di- or trinucleotide sequences. Which among these methylation motifs are found predominantly in case of protein-coding genes in plants? H stands for A, T or C.
Select an option to attempt
Correct Answer: Option B
Explanation
DNA methylation context in plants (where H = A, T, or C):• CpG: Most conserved context; maintained by MET1 (homologue of mammalian DNMT1).• CpHpG: A plant-specific context; maintained by CMT3 methyltransferase.• CpHpH: Another plant-specific context; established by DRM2 and maintained by CMT2.For protein-coding gene bodies in plants, CpHpG and CpHpH methylation predominates (in addition to CpG). This is distinct from mammals, which rely almost exclusively on CpG methylation. CpGpG is not a standard methylation context and is a distracting option. Answer: CpHpG and CpHpH (Option 2).