TATA box involved in the initiation of transcription is located in the:
TATA box involved in the initiation of transcription is located in the:
Select an option to attempt
Correct Answer: Option A
Explanation
TATA box: location and function:The TATA box (consensus: TATAAA) is a core promoter element:• Location: ~25-30 bp UPSTREAM of the transcription start site (TSS), in the PROMOTER region.• Function: Recognised by TBP (TATA-Binding Protein), the universal component of TFIID, which nucleates pre-initiation complex assembly.• TATA-box containing genes: often highly regulated, tissue-specific, or stress-responsive.• ~30% of eukaryotic promoters have a TATA box; the rest use other core elements (Inr, DPE, MTE, BRE).Distractors:• Enhancer: a cis-regulatory element that can be far from the promoter and in any orientation; it increases transcription but is NOT where TATA box is found.• Exon: part of the mRNA coding/flanking sequence.• Intron: non-coding intervening sequence; not part of the promoter.Answer: Promoter region (Option 1).