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Molecular Biology PYQs

41 previous year questions across 16 subtopics · answers and explanations included

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Showing 41 questions · page 2 of 3

21

Met-Ile-Val-His-Tyr was the sequence of a hypothetical peptide. Assuming that there are two possible codons each for His, Val and Tyr, one possible codon for Met, and four possible codons for Ile, the number of possible nucleotide sequences coding for this…

MediumView answer

22

Which one of the following markers is NOT routinely used for DNA fingerprinting?

MediumDNA Fingerprinting & Polymorphism MarkersView answer

23

DNA isolated from four unidentified species of bacteria - A, B, C and D has been estimated to have 38%, 26%, 24% and 12% thymine, respectively. One of these four species was isolated from a hot spring (64°C). Identify the candidate which is most likely to be…

MediumDNA Base Composition & GC ContentView answer

24

Given below are two statements: Statement I: Polycistronic mRNAs are found in archaea and bacteria. Statement II: Plastid genes in eukaryotes have only mono-cistronic mRNA. In the light of the above statements, choose the most appropriate answer from the…

MediummRNA Structure - Polycistronic vs MonocistronicView answer

25

Which one of the following enzymes help the DNA to overcome the tension generated by the unwinding during replication?

MediumDNA Replication - TopoisomerasesView answer

26

Which one of the following types of mutations can lead to a major change in the encoded protein? A. Insertion of a single nucleotide near the end of the coding sequence. B. Removal of a single nucleotide from the beginning of the coding sequence. C. Deletion…

MediumMutations & Reading Frame ShiftsView answer

27

Identify the incorrect pair

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28

In the cloverleaf structure of tRNA, the cognate amino acid is attached at

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29

Digestion of a 5 Kb linear DNA with BamHI leads to the generation of two fragments of size 2 Kb and 3 Kb, while digestion of the same DNA with HindIII generates 3 fragments of 0.7, 0.8 and 3.5 Kb. When the same DNA is cut with both BamHI and HindIII enzymes…

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30

Which of the following is NOT a feature of bacterial DNA replication?

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31

ATP with \gamma - ^{32}P can be used for which of the following type of reaction?

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32

A class of temperature sensitive E. coli mutants defective in DNA replication were identified that ceased replication immediately upon increase in temperature. Which of the following processes are likely to be defective in these mutants?

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33

Which one among the following is an important constituent of RNA induced silencing complex in plants?

MediumRNA Interference & RISC ComplexView answer

34

Sequence-specific recognition of DNA by proteins occurs primarily through the

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35

For a tetranucleotide sequence, the number of possible combinations using A, T and G are

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36

The technique used to locate specific genes in chromosomes is

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37

Which one of the following involves RNA Editing?

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38

A student added a 5' exonuclease enzyme instead of a restriction enzyme to digest his purified plasmid DNA sample. What is he likely to observe when he runs his plasmid digest on an agarose gel?

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39

If a nonsense mutation is present in the LacZ gene of the lac operon, the mRNA of \beta -galactosidase would

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40

DNA glycosylases are DNA repair enzymes involved in

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