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Biochemistry PYQs

105 previous year questions across 53 subtopics · answers and explanations included

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Showing 105 questions · page 1 of 6

1

500 mg of a drug (Molecular weight 100) was intravenously injected into an individual having a blood volume of 5 liter. The drug is neither absorbed by the tissues nor it is excreted. If the drug is metabolized so that half of it is degraded in eight hours,…

MediumPharmacokinetics & Drug CalculationsView answer

2

Which of the following is a non-reducing sugar?

EasyView answer

3

While measuring the potassium concentration in a drug formulation, the technologist took 10 µl of the sample and mixed it with 90 µl of test buffer. From the resulting solution, he took 5 µl and measured its total potassium content as 25 ng. What would be…

MediumDilutions & Concentration CalculationsView answer

4

You are given a 5 mM solution of sucrose. If you hydrolyse it by adding equal volume of 10 mM HCl, what would be the final concentration of glucose and fructose in the hydrolysate?

MediumSolution Chemistry & DilutionsView answer

5

The egg white protein, ovalbumin, is denatured in a hard-boiled egg. Which of the following is least affected?

EasyView answer

6

You are measuring blood glucose level by glucose oxidase method. Following are the absorbance values that you got for the standard and the test sample: [Table]

MediumSpectrophotometry & Glucose EstimationView answer

7

The introduction of the nonpolar molecule (toluene) into water results in:

MediumThermodynamics & Hydrophobic EffectView answer

8

You are preparing a 500 ml solution containing 50 mM Tris (FW 120) buffer, 10 mM NaCl (FW 58.5), 5 mM EDTA (supplied solution is 500 mM). The quantity of each of the ingredients would be:

MediumBuffer Preparation & Solution ChemistryView answer

9

Someone tells you that the pH of a solution is minus 2. Which one of the following is false?

MediumView answer

10

Match the items in List I with the items in List II: [Table] Choose the correct answer from the options given below:

MediumMetabolic Pathways - Match the FollowingView answer

11

Histones

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12

Which one of the following statements is true with respect to optical activity?

MediumStereochemistry & Optical ActivityView answer

13

Which one of the following compound(s) is/are NOT the carbon source of acetyl Co-A?

MediumAcetyl-CoA MetabolismView answer

14

Enzymes bind their substrates via

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15

Which of the following is true for acetyl-CoA?

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16

In enzyme kinetics, if the enzyme concentration is doubled

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17

Trypsin cleaves a protein at the

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18

A mixture of homotetramer 'X' and heterodimer 'Y' with identical molecular weight were resolved on SDS-PAGE. It gives three bands on a gel with molecular weights 40 kDa, 60 kDa, and 100 kDa. The native molecular weight (in kDa) of the homotetramer 'X' is

HardView answer

19

The molecular weight of Val and Ser are 117 Dalton and 105 Dalton, respectively. Val and Ser form a dipeptide Val-Ser. The molecular weight (in Daltons) of the dipeptide is

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20

An enzyme is governed by Michaelis-Menten Kinetics. The apparent K_M increases four fold due to the addition of inhibitor but the reaction rate declines by 50%. The substrate concentration in the reaction is:

MediumEnzyme Kinetics - Michaelis-MentenView answer