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Biochemistry PYQs

105 previous year questions across 53 subtopics · answers and explanations included

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Showing 70 questions · Medium · page 2 of 4

21

Ligands 'A' and 'B' bind to protein 'P' with dissociation constants of 1 nM and 100 nM, respectively. Which of the following is true?

MediumView answer

22

What is the concentration of D_2O in heavy water (density 1.11 g/ml)?

MediumSolution Chemistry & MolarityView answer

23

What is the molarity of 100 g Glycine (75 Daltons) dissolved in 1 liter water?

MediumMolarity & Solution CalculationsView answer

24

What will be the molecular weight of the tri-peptide Trp-Gly-His? Molecular weights of Trp, Gly, and His are 204.2, 75.07, and 155.2 respectively.

MediumPeptide Molecular Weight CalculationsView answer

25

Synthesis of which of the following lipids is completed in the Golgi bodies

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26

What, if any, is the difference between the molecular weights of molecule A (left) vs molecule B (right)? [Image]

MediumMolecular Weight of Organic CompoundsView answer

27

What may be the simplest and most inexpensive way to know that the product is formed in the reaction given below? [Image]

MediumOrganic Chemistry Reactions & DetectionView answer

28

What will be the final concentration of the solute when 10 ml of its 10 M solution is mixed with 990 ml solvent?

MediumSolution Dilutions & ConcentrationView answer

29

How many chiral centers are there in each of these two molecules? [Image]

MediumStereochemistry & Chiral CentersView answer

30

The CO-NH moiety between two C-alpha atoms constitutes the Peptide bond. The measured bond lengths (Angstroms) are: C(alpha)-CO (1.51); C=O (1.24); C-N(1.33); N-C(alpha)1.46. In which of these, there is a decrease from the expected bond length due to partial…

MediumProtein Structure - Peptide BondView answer

31

Which one of these is a metal containing Vitamin?

MediumVitamins & CofactorsView answer

32

How many different kinds of post translational modifications are present in this peptide? [Image]

MediumPost-Translational ModificationsView answer

33

Given the molecular structure of glucose, the molecular formula and molecular weight of maltose will be: [Image]

MediumCarbohydrate Structure & Molecular FormulaView answer

34

What will be the absorbance of a 1 mM solution of molecule X whose molar extinction coefficient is 1000 M^{-1}cm^{-1} & path length of the cuvette used is 1 cm?

MediumSpectrophotometry - Beer-Lambert LawView answer

35

Amide bonds between two amino acids (as shown below) are generally in trans-conformation. The atoms are labeled as A1 through A6. The angle measured for defining the trans-conformation of the amide bond is the angle between: [Image]

MediumProtein Structure - Peptide Bond ConformationView answer

36

A protein with 10 lysines and 2 arginine residues was digested with trypsin and the peptide mixture was resolved on an SDS-PAGE. After silver staining, 10 bands were detected instead of 13. Select the plausible reasons from the following: A. Some of the…

MediumProteolysis & Trypsin DigestionView answer

37

15 to 30% of collagen residues are 4-hydroxyproline residues (Hyp). When rats are fed with ¹⁴C labeled Hyp, the collagen produced by them is not radioactive, but when they are fed with ¹⁴C labeled Proline, the collagen produced is radioactive. What is the…

MediumCollagen & Hydroxyproline BiosynthesisView answer

38

The probe used to analyse glycoproteins is

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39

A protein completely unfolds in 8 M Urea. The stability of the folded state in water is calculated to be 8 kCal/mole at 25°C. What is the likely ΔG of the following reaction in 8 M Urea? A(native) → A(unfolded) Choose the correct answer :

MediumProtein Folding & ThermodynamicsView answer

40

A following reaction is occurring in a test tube: A + B ⇌ C 100 nM solution of A is incubated with an equal volume of 100 nM solution of B and left at 25°C till the equilibrium is reached. Finally, when the concentration of A is measured, it is found to be…

MediumChemical Equilibrium & Reaction KineticsView answer