Topic

Bioinformatics PYQs

23 previous year questions across 16 subtopics · answers and explanations included

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One question at a time, instant feedback, score at the end.

Showing 18 questions · Medium

1

Which one of the following CANNOT be used for progressive global multiple sequence alignment?

MediumMultiple Sequence Alignment ToolsView answer

2

BLOSUM matrix is used for

MediumView answer

3

Given below are two statements one is labelled as Assertion A and the other is labelled as Reason R: Assertion A: The dot matrix method of sequence alignment is a very basic method that should be used first, before other more complex methods. Reason R: The…

MediumSequence Alignment - Dot Matrix MethodView answer

4

Given below are two statements: Statement I: An alignment is generated by starting at the ends of the two sequences and attempting to match all possible pairs of characters between the sequences and by following a scoring scheme for matches, mismatches, and…

MediumPairwise Sequence Alignment & Scoring MatricesView answer

5

Which of the following represents a quantitative measure of the structural similarity between two proteins?

MediumView answer

6

Given below are two statements: Statement I: RNA secondary structure is composed primarily of double-stranded RNA regions formed by folding of the single-stranded molecule back on itself. Statement II: Like protein secondary structure, RNA secondary…

MediumRNA Secondary Structure PredictionView answer

7

Which one of the following DOES NOT represent known interactions of RNA secondary structural elements?

MediumRNA Structural InteractionsView answer

8

Which one of the following can be considered as a Data Matrix?

MediumData Structures in R/ProgrammingView answer

9

Which one of the following can be considered as an Atomic Vector?

MediumData Structures in R - Atomic VectorsView answer

10

Which one of the following lines of unix commands can tell you the number of lines in a file?

MediumUnix/Linux Commands for BioinformaticsView answer

11

Which one of the following is NOT a Data Type?

MediumData Types in ProgrammingView answer

12

Which one of the following is comparatively the best E-value to a pairwise sequence match?

MediumBLAST & E-value InterpretationView answer

13

Your friend runs a BLASTp on his unknown sequence and finds a match with E-value of 3 with a target. What does this mean?

MediumBLAST Search & Statistical SignificanceView answer

14

During analysis of Next-Gen Sequencing data, what is the advantage of BAM files over SAM files?

MediumNGS Data Formats - BAM vs SAMView answer

15

The measure of similarity between two structurally aligned macromolecules is:

MediumStructural Bioinformatics - RMSDView answer

16

Which command is suitable to list out all the directories in the working directory, in linux/unix environment?

MediumUnix/Linux CommandsView answer

17

Which regions of the genome are best suited for generating DNA Barcodes for species identification?

MediumDNA Barcoding & Species IdentificationView answer

18

Which one of the following is true for PAM250 Scoring Matrix?

MediumPAM Scoring MatrixView answer