DBT JRF 2020
Official DBT JRF 2020 previous year paper for practice and preparation.
200 questions 180 min 300 marks
Attempt as a timed mock test All questions with answers
- Q1The Freund's complete adjuvant is a mixture of
- Q2Which of the following is a non-reducing sugar?
- Q3Keshav and Kunal are good in Maths and Chemistry. Sumit and Keshav are good in Maths and Biology. Vineet and Kunal are good in Cricket and Chemistry. Sumit,…
- Q4In the first semester course work at the Biotech Institute, 50 students signed up for both Genetics and Statistics, and 90 students signed up for either…
- Q5Which of the following is NOT true?
- Q6The egg white protein, ovalbumin, is denatured in a hard-boiled egg. Which of the following is least affected?
- Q7Synthesis of majority of lipids in a cellular system occurs in the
- Q8What is the probability of getting 53 Sundays in a 'Leap' year?
- Q9What will be the generation time of a culture with a specific growth rate constant of 0.01 \, \text{min}^{-1} ?
- Q10The most important step of an automated DNA sequencing reaction is
- Q11Someone tells you that the pH of a solution is minus 2. Which one of the following is false?
- Q12The fruit of a particular tree species formed the predominant diet of the dodo. After the dodo became extinct, that tree species also became extinct. Which of…
- Q13Histones
- Q14What is the frequency with which a 4 bp cutter will cut the DNA, assuming random distribution of bases in the genome?
- Q15Primary cilia biogenesis typically starts at the
- Q16Enzymes bind their substrates via
- Q17The number of squares and triangles in the following figure is [Image]
- Q18Which of the following is true for acetyl-CoA?
- Q19The enzyme used in glucometers to estimate blood glucose levels is
- Q20During growth, the diameter of a Staphylococcus bacterial cell increases by 5%. The specific surface area (defined as surface area per unit volume)
- Q21In enzyme kinetics, if the enzyme concentration is doubled
- Q22Chlorine is assigned an atomic weight of 35.5. This is due to
- Q23Trypsin cleaves a protein at the
- Q24Single stranded DNA can be separated from double stranded DNA efficiently using
- Q25A mixture of homotetramer 'X' and heterodimer 'Y' with identical molecular weight were resolved on SDS-PAGE. It gives three bands on a gel with molecular…
- Q26The molecular weight of Val and Ser are 117 Dalton and 105 Dalton, respectively. Val and Ser form a dipeptide Val-Ser. The molecular weight (in Daltons) of…
- Q27What is the correct value of X? [Image]
- Q28The temperature of media post sterilization drops from 100°C to 60°C in 40 min by simply keeping it on the lab bench and allowing slow atmospheric cooling to…
- Q29Which of the following is/are critical for genome replication?
- Q30Find the next number in the series 23, 30, 38, 47, 57
- Q31Nucleic acid structures are stabilized by
- Q32A buffer contains 10% glucose, 20 mM Tris, and 50 mM HCl. For making 1 litre of buffer from the following stock solutions – 50% glucose, 1 M Tris, and 1 M…
- Q33Using only random VDJ recombination, from 40 V, 30 D and 6 J gene segments, the number of possible variable regions of the resulting antibody would be
- Q34The aluminium bronze alloy consists of copper and aluminium in the ratio of 10:1 by weight. If an object made of this alloy weighs 77 Kilograms (Kg), how many…
- Q35Choose the correct alternative from the series on the right to complete the missing figure in the series on the left. [Image]
- Q36The role of DNA ligase in DNA replication is
- Q37Which of the following is a method of investigating the sequence specificity of DNbinding proteins in vitro?
- Q38How many peptide fragments can be generated from the complete digestion of the polypeptide AGRCDKCQANRSLMNF with trypsin?
- Q39Bacteria protect themselves from phages by producing the following enzymes which fragment the phage genome
- Q40The genetic codon is a triplet and there are 64 codons. How many codons would be possible if the codon is a doublet?
- Q41How much sodium hydroxide will you weigh to prepare 0.25 L of 3 M solution?
- Q42A student made 0.15 M solution of copper sulphate. The absorbance of the solution was found to be 0.3 when using a cuvette with a path length of 1 cm. Copper…
- Q43Eight 3rd year students can finish an experiment in 15 days and eighteen 1st year students can complete the same experiment in 10 days. If all these students…
- Q44Two particles are moving back and forth in a 10 m long tube. Particle 'P' is moving at a speed of 5 m/s and particle 'Q' at a speed of 2 m/s. Consider that…
- Q45Denaturation of DNA is a
- Q46A, B, C and D are to be seated in a row. But C and D cannot be together. Also B cannot be at the third place. Which of the following must be false?
- Q47While working in the lab, you forgot to keep enzymes back in the fridge. Which of the following enzyme will be least affected on being left outside at room…
- Q48Which of the following is NOT a rational grouping of amino acids based on their polarity properties?
- Q49Ligands 'A' and 'B' bind to protein 'P' with dissociation constants of 1 nM and 100 nM, respectively. Which of the following is true?
- Q50Mr. Thomas invested an amount of Rs.13,900 divided in two different schemes A and B at the simple interest rate of 14% p.a. and 11% p.a., respectively. If the…
- Q1The innate immune system recognizes Pathogen Associated Molecular Patterns (PAMPs) through activation of
- Q2Which of the following plant hormones employs a phosphorelay system to regulate gene expression?
- Q3Hepatitis B is caused by a
- Q4Synthesis of which of the following lipids is completed in the Golgi bodies
- Q5Which of the following marine phototrophs can utilise carbon-dioxide as the carbon source?
- Q65th June is observed as
- Q7What is agent Orange?
- Q8Which one of the following can be extended by Klenow enzyme upon addition of dNTPs and Mg2+ ?
- Q9During genome engineering process, the role of Flippase enzyme in the next round of modification in the target gene is to
- Q10The first drug approved by FDA of USA, that was produced through genetic engineering was
- Q11Fragile X syndrome is caused by a fragile site at the end of the long arm of X chromosome. Such a disorder is
- Q12In Transmission Electron Microscope (TEM), a beam of electrons interact with the specimen to form image as
- Q13A major organism used in commercial bioleaching for copper recovery is
- Q14A bacterial population, growing in batch culture, increases from 1000 cells to 10,00,000 cells in 5 hours. What is the generation time of the bacteria?
- Q15A fermentation medium is being cooled from 70 °C to 32 °C in a double pipe heat exchanger. Fluid flowing counter currently with this stream is heated from 20…
- Q16Consider a bacterium that grows with doubling time of 20 min in the exponential phase of its growth cycle and acquire 10 random mutations in its genome in…
- Q17What is the use of Aminopterin in hybridoma production?
- Q18What is Endoreduplication?
- Q19The probe used to analyse glycoproteins is
- Q20One centimorgan is defined as the genetic distance between two loci with a statistically corrected recombination frequency of
- Q21The sequence CGAATTTGG is matched globally with four sequences in a database. The sequence that will give the highest similarity score taking match =1,…
- Q22Which of the combination of gases is finally produced during anaerobic digestion?
- Q23Which histone is NOT a part of the nucleosomes?
- Q24If four atoms A, B, C and D are connected linearly and there is rotation possible along bond BC, dihedral angle on this bond is described as
- Q25Which of the following are NOT transcribed by RNA polymerase II?
- Q26'Cybrids' are produced by
- Q27For a microbial culture, if the doubling time is 0.231 h, the specific growth rate (in h^{-1} ) will be (assume that the endogenous metabolism is negligible)
- Q28The mature anther wall comprises an epidermis followed by a layer of radially elongated cells with fibrous bands of callose called endothecium whose function is
- Q29All the vaccines mentioned below are attenuated or inactivated whole pathogen except
- Q30In an exponentially growing batch culture of Saccharomyces cerevisiae, the cell density is 30 gL^{-1} (DCW), the specific growth rate ( \mu ) is 0.4 h^{-1}…
- Q31Which of the following disorders does not show sex-linked inheritance?
- Q32Met-Ile-Val-His-Tyr was the sequence of a hypothetical peptide. Assuming that there are two possible codons each for His, Val and Tyr, one possible codon for…
- Q33Choose the correct order in terms of pKa
- Q34Which of the following yeast is used for the production of riboflavin?
- Q35The enzyme-linked immunospot (ELISPOT) assay is highly sensitive because it can measure
- Q36Immobilization of enzymes to water insoluble, anionic porous carriers often results in an apparent shift in the pH optima of the enzyme. The physico-chemical…
- Q37Which of the following is a chemotherapeutic drug obtained from marine source?
- Q38Cellulose is a linear polymer of glucose with
- Q39Which of the following microorganism is used for commercial production of dextran?
- Q40The amino acid residue with the least preference for any quadrant in the Ramachandran map is
- Q41Which class of phytochromes is highly abundant in etiolated seedlings and is also light labile?
- Q42Which of the following amino acids is most likely to disrupt an \alpha -helix?
- Q43A combination of gametes that can be formed by the genotype AaBbCcDdEeFfGg are
- Q44Which part of a plant would be most suitable for raising virus-free plants for micropropagation?
- Q45BLOSUM matrix is used for
- Q46The methods utilized to determine the three dimensional structure of proteins are
- Q47What are the cellular sites for protein glycosylation?
- Q48Which of the following is NOT used as a biopesticide?
- Q49Identify the incorrect pair
- Q50The \beta -sheet rich structure of prion protein represents the